During the ‘Knightfall’ storyline, Bane goes to Gotham City with the intention of hunting Batman and defeating him. Deciding he wants Batman in his weakest physical and psychological state he attacks Arkham Asylum allowing its deranged inmates to escape. This includes all the major-league Gotham crazies, the Joker, Two-Face, the Riddler, the Scarecrow etc) to escape into Gotham City. Consequently, Batman is forced to recapture the escapees, a mission that takes him three months and drives him to mental and physical collapse.
Exhausted, Batman returns to his home in Wayne Manor, only to find Bane waiting for him. Bane attacks Batman, beating him to within an inch of his life. Not content with the defeat of his nemesis, Bane decides not to kill Wayne but to let him live with his ‘shame’. He then raises him up overhead and breaks his back over one knee, leaving him a paraplegic. In the comics, Bane is the only villain to have ‘Broken the Bat’. (This iconic moment is incorporated in the Christopher Nolan film ‘The Dark Knight Rises.’
Eventually, Bruce Wayne would return but is haunted by the memory of the man who managed to hunt him down and break him. The two have since clashed many times in the DC stories, sometimes as enemies, sometimes as allies. The character of Bane has since gone in many directions from taking over Gotham and becoming a hero, to trying to unravel his past, most notably the identity of his father.